NAMs in Drug Development
Human-relevant science.
Informed drug development.
New approach methodologies (NAMs) are experimental and computational approaches used to study drug effects and safety, aiming to improve human relevance and reduce reliance on animal testing.
NAMs Insights is a specialist website covering research, methods and regulatory developments in NAMs for drug discovery and evaluation worldwide.
A four-platform comparison combined lipid imaging, liver-function measurements, expression profiling and CYP assays. Lipid accumulation did not uniformly reduce drug metabolism, and differences depended on the model and donor.
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